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Scientist Analytical Characterization
Contract: Worcester, Massachusetts, US
Salary Range: 55.00 - 60.00 | Per Hour
Job Code: 371750
End Date: 2026-10-18
Days Left: 27 days, 9 hours left
Hi there, This is Siddhi, Talent Expert with Collabera LLC. Hope this message finds you well! We're hiring for Top performers encouraged to apply positions are filling fast! If interested, Let's connect and don't miss out apply today and let's talk about your next big opportunity!
Email: siddhi.kadakia@collabera.com | Phone: (847)-440-1112.
Position Details:
Email: siddhi.kadakia@collabera.com | Phone: (847)-440-1112.
Position Details:
Client Industry: Pharmaceutical;
Job Title: Scientist III – Analytical Characterization
Location: Worcester, MA 01605
Duration: 12 Months Contract (++ possibility of extension based on performance and business needs)
Shift: On-site
Pay Range: $55.00 to $60.00 per hour
Job Title: Scientist III – Analytical Characterization
Location: Worcester, MA 01605
Duration: 12 Months Contract (++ possibility of extension based on performance and business needs)
Shift: On-site
Pay Range: $55.00 to $60.00 per hour
HM's Top 3 Priorities
1. Mass Spectrometry expertise
2. Independence & scientific maturity – able to design and execute experiments with high-quality/data integrity
3. Communication skills – able to clearly communicate scientific findings internally and cross-functionally
2. Independence & scientific maturity – able to design and execute experiments with high-quality/data integrity
3. Communication skills – able to clearly communicate scientific findings internally and cross-functionally
Sourcing Focus
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Large Molecule/Biologics + Protein Characterization + LC-MS/Mass Spectrometry + Intact Protein/Peptide Mapping + Orbitrap + HPLC/ÄKTA
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Key screening: A candidate with fewer years but directly relevant protein/biologics mass spectrometry experience is more relevant than someone with many years of small-molecule analytical chemistry experience.
What are the top 3-5 skills, experience or education required for this position:
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Perform separation assays such as HPLC/UPLC chromatography
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Perform fractionation using AKTA
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Perform LC-MS experiments on intact protein
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Fundamental understanding of protein structure, post-translational modifications, and analytical methods used for protein characterization
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Excellent written communication, oral communication, organization, and multitasking skills
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We are searching for a highly motivated Scientist to join our Analytical Development team in Worcester, MA. Our team is responsible for the development, qualification, and execution of analytical methods to provide product and process understanding for biological entities from discovery through commercial stages.
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As a Scientist, you will be a part of the Analytical Characterization Group (ACG) within the Analytical Development Department. ACG focuses on providing routine, investigative, and in-depth characterization analyses of biologics to support product and process development for early-phase, late-phase, and commercial programs using liquid chromatography mass spectrometry (LC-MS), spectroscopy and various other biophysical assays.
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The successful candidate will contribute to the development and performance of analytical assays and will contribute to the continuous improvement and innovation within ACG and the Analytical Development Department.
Key Responsibilities:
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Perform mass spectrometry analyses (i.e., intact/reduced mass analysis by LC-MS and peptide mapping by LC-MS) of biologics to provide sequence verification and post-translational modification profiles.
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Independently perform separation methods (e.g., fractionation & analysis of variants) using HPLC and AKTA
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Perform biophysical methods (e.g., DSC) of biologics to support characterization studies.
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Design and execute experiments for method development and/or investigations.
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Support process development by performing raw material analysis using vibrational spectroscopy and executing metabolomics experiments using mass spectrometry.
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Generate and communicate precise, reliable, and reproducible data in a timely manner.
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Organize and document experiments and results in an electronic laboratory notebook.
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Draft protocols, method development reports, and technical characterization reports.
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Maintain lab equipment.
Qualifications:
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Bachelors or Masters in chemistry, biology, biochemistry or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting.
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Hands-on experience with protein mass spectrometry, liquid chromatography, capillary electrophoresis and protein biophysical characterization.
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Knowledge of HPLC or AKTA instrumentation
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Fundamental understanding of protein structure, post-translational modifications, and analytical methods used for protein characterization.
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Working knowledge of bioinformatics tools to process and analyze mass spectrometry data is highly desirable.
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Knowledge of vibrational spectroscopy (e.g., IR, NIR and Raman) and multivariate analysis is desirable.
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Proficient with Windows 10 and MS Office (Outlook, Excel, Word, and PowerPoint).
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Excellent written communication, oral communication, organization, and multitasking skills.
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Hardworking and motivated to drive both efficiency and quality.
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Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials.
What HM Is Looking For
- Primary must-have: Hands-on Mass Spectrometry / LC-MS experience
- Must have large-molecule / biologics / protein characterization experience.
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NO small-molecule-only profiles.
- Experience with intact protein, subunit and/or peptide mapping using LC-MS is highly relevant.
- Thermo Orbitrap experience is strongly preferred and will reduce training time, but is not mandatory.
- HPLC/UPLC and/or ÄKTA fractionation experience is valuable.
- Limited ÄKTA experience is acceptable if the candidate has strong mass spectrometry experience.
- Candidate must have genuine hands-on laboratory experience.
Nice-to-Haves
- Protein biophysical characterization.
- DSC – Differential Scanning Calorimetry
- CD – Circular Dichroism
- AUC – Analytical Ultracentrifugation
- Broader chromatography/protein fractionation experience.
Ideal Candidate Profile
- Early-to-mid-career Scientist / Analytical Scientist / Protein Characterization Scientist / Mass Spectrometry Scientist.
- PhD candidates, including relevant postdoctoral experience, are acceptable.
- BS/MS candidates with strong relevant experience are also acceptable.
- HM is flexible on exact years based on education + technical depth.
- Generally, <10 years relevant experience is the likely sweet spot.
- Avoid heavily senior/established 10–15+ year profiles unless the experience and career expectations clearly align.
Benefits:
The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan, life insurance, long-term disability insurance, short-term disability insurance, paid parking/public transportation, (paid time , paid sick and safe time , hours of paid vacation time, weeks of paid parental leave, paid holidays annually – These all are subject to applicable eligibility).
The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan, life insurance, long-term disability insurance, short-term disability insurance, paid parking/public transportation, (paid time , paid sick and safe time , hours of paid vacation time, weeks of paid parental leave, paid holidays annually – These all are subject to applicable eligibility).
Job Requirement
- Mass Spectrometry
- LC-MS
- LC-MS/MS
- Protein Characterization
- Biologics
- Large Molecules
- Intact Protein Analysis
- Peptide Mapping
- Post-Translational Modifications
- Orbitrap
- HPLC
- UPLC
- ÄKTA
- Chromatography
- Protein Fractionation
- Analytical Development
- Protein Structure
- Biophysical Characterization
- DSC
- Circular Dichroism
- Analytical Ultracentrifugation
- Bioinformatics
- Mass Spec Data Analysis
- Method Development
- Method Qualification
- Data Integrity
- Electronic Lab Notebook
- Pharmaceutical
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Chemistry
Reach Out to a Recruiter
- Recruiter
- Phone
- Siddhi Kadakia
- siddhi.kadakia@collabera.com
Apply Now
Apply Now
