To Discuss more about this job opportunity, please reach out to Anwesha Mohapatra (LinkedIn URL -Anwesha Mohapatra - Collabera | LinkedIn), email your updated resume at Email - anwesha.mohapatra@collabera.com. Thank you!

Pay Range: $55/hr to $60/hr

Job Title: Scientist II

Location: South San Francisco, CA 94080

Work Type: Onsite

Contract Duration: 12 months with possible extension

Job Summary:

• The Scientist II will support biologics drug discovery and engineering within a dynamic large enterprise environment.
• The role will focus on the design and execution of in vitro display technologies for lead antibody identification and optimization.
• The scientist will contribute to the generation of in vitro and in vivo data packages supporting proof of concept activities.
• The position requires strong expertise in molecular biology, cell biology, antibody discovery, binding assays, and protein engineering concepts.
• The successful candidate will analyze, document, and communicate experimental data while collaborating effectively with cross functional research teams.

Key Responsibilities:

• Design and execute in vitro antibody discovery display technologies to support lead identification and optimization.
• Perform binding assays including ELISA, flow cytometry, and surface plasmon resonance.
• Apply molecular and cell biology techniques including molecular cloning, sequence analysis, bacterial culture, yeast culture, and mammalian cell culture.
• Support antibody engineering and optimization activities including affinity modulation, humanization, and liability engineering.
• Collaborate with research teams to generate in vitro and in vivo data packages supporting proof of concept activities.
• Analyze experimental results and effectively document and communicate scientific findings.
• Present research findings and scientific conclusions in group settings.

Required Qualifications:

• Bachelor of Science or Master of Science degree in Biology or a related scientific field.
• Typically 5 or more years of relevant experience with a Bachelor of Science degree or 2 or more years of relevant experience with a Master of Science degree.
• Hands on experience with in vitro antibody discovery display technologies such as phage display or yeast display.
• Direct experience with binding assays such as ELISA, flow cytometry, or surface plasmon resonance.
• Strong molecular and cell biology skills including molecular cloning, sequence analysis, bacterial or yeast culture, and mammalian cell culture.
• Familiarity with protein structure, antibody affinity, antibodies, and antibody fragments.
• Strong data analysis, documentation, written communication, and presentation skills.

Preferred Qualifications:

• Experience with antibody engineering and optimization including affinity modulation, liability engineering, and humanization.
• Experience with antibody library design and construction.
• Experience with mammalian cell culture and multiplex flow cytometry.
• Experience with automation of biologics discovery processes.
• Proficiency with Prism, Geneious, or Genedata.
• Proficiency with MS Office Suite including Excel, PowerPoint, and Word.

Benefits: The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan, life insurance, long-term disability insurance, short-term disability insurance, paid parking/public transportation, (paid time , paid sick and safe time , hours of paid vacation time, weeks of paid parental leave, paid holidays annually - AS Applicable)